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8. Mucinous carcinoma of the colon (human). Only a few cancer cells are seen in virtual "lakes" of mucin (empty-looking spaces). Hematoxylin and eosin, x 3 0 0 . induced neoplasms differs in different species and within the same species. , 1983). As described previously, adenomatous polyps are characterized by a neoplastic component (head) and a fibrovascular connective tissue stalk that does not show features of neoplasia (Fig. 3). Careful examination of the induced exophytic lesions in animals as well as published photomicrographs of adenomatous polyps reveals that most of these lesions do not fit the criteria for adenomatous polyps.

J. Pathol. Bacteriol. 35, 3 2 3 - 3 3 2 . Elsayed, A. , and Shamsuddin, Α. Κ. M. (1986). Agglutinin as a marker for preneoplastic and neoplastic changes in the human and rat colon. Proc. Am. Assoc. Cancer Res. 27, 2 0 1 . Falterman, K. , Hill, C. B . , Markey, J. C , Fox, J. , Jr. (1974). Cancer of the colon, rectum and anus—A review of 2313 cases. Cancer 34, 9 5 1 - 9 5 9 . Fenoglio, C. , and Lane, N. (1974). The anatomical precursor of colorectal carcinoma. Cancer 34, 8 1 9 - 8 2 3. Iseri, Ο.

Gann Monogr. Cancer Res. 3 1 , 5 9 - 6 6 . Snyder, D. , Heston, J. , Meigs, J. , and Flannery, J. T. (1977). Changes in site distribution of colorectal carcinoma in Connecticut, 1 9 4 0 - 1973. Am. J. Dig. Dis. 22, 7 9 1 - 7 9 7 . Spratt, J. , and Ackerman, L. V. (1962). Small primary adenocarcinomas of the colon and rectum. J. Am. Med. Assoc. 179, 3 3 7 - 3 4 6 . Swartzendruber, D. C , and Richter, C. Β. (1980). Mucous and argentaffin cells in colonic adenocarcinomas of tamarins and rats. Lab.

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