By Georges Mathé (auth.), Georges Mathé (eds.)
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Additional info for Aseptic Environments and Cancer Treatment
Patients in hospitals receiving therapy with cytotoxic and immunosuppressive drugs are at high risk to infection by a particularly large variety of organisms both endogenous and exogenous. At the present time, one in twenty patients entering a hospital will acquire an infection; this incidence has remained unchanged since the pre-chemotherapy and antibiotic era (WISE, SWEENEY, HOUPT, and WADDELL, 1959; CORIELL, BLAKEMORE, and MCGARRITY, 1968). A recent study at a university hospital demonstrated that approximately one-third of the clinical infections were due to cross infections and two-thirds of these were caused by gram-negative organisms (McNAMARA, BELOWS, and TUCKER, 1967).
2. Air flow in the new portable laminar flow unit tIrIng to work with patients in the unit. Cleaning and maintenance are problems, particularly when the unit is occupied by a patient. For some years industrial firms and government agencies concerned with hardware for space exploration have utilized particle-free rooms for the assembly of space capsules and instruments (AUSTIN and ZIMMERMAN, 1965). The concept utilized in these particle-free rooms, that of laminar air flow combined with high efficiency filtration, has been applied to operating rooms (CORIELL, McGARRITY, and HORNEFF, 1967).
9. , FREIREICH, E. : Studies of a patient isolator unit and prophylactic antibiotics in cancer chemotherapy. Cancer 22, 1018-1026 (1968). 10. - Laminar air flow unit for patients undergoing cancer chemotherapy. Germ-free Biology. Plenum Press 1969. 11. : Microbiological studies of a laminar air flow unit for patients. Arch. Environmental Health 19, 798-805 (1969). 12. - FREIREICH, E. : Studies of patients in a laminar air flow unit. Cancer 24, 972-980 (1969). Studies of Components of Patient Protection Programs: Non-absorbable Antibiotics and Low Bacterial Diets E.