By Dennis F. Kohn, Sally K. Wixson, William J. White, G. John Benson
Anesthesia and Analgesia in Laboratory Animals focuses solely at the particular anesthetic, analgesic, and postoperative care specifications linked to experimental surgical procedure. backed by means of the yank university of Laboratory Animal medication, this informative paintings presents the reader with brokers, tools, and methods for anesthesia and analgesia that determine humane and winning procedural results. Key positive aspects * specializes in a large choice of animal species utilized in learn * presents a entire review of the pharmacology of anesthetics and analgesics * contains tracking of analgesia and anesthesia * Organizes issues by means of species for brokers and strategies of offering anesthesia, analgesia, and post-op care to animals * No different American textual content is dedicated solely to this subject
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This practice can easily result in mixtures of two anesthetics and misidentifying the contents of the vaporizer. Vaporizers should always be clearly labeled and only contain the designated anesthetic (Dorsch and Dorsch, 1994). B. Molecular Weight All of the inhaled anesthetics have similar molecular weights with the exception of nitrous oxide and ether (Table I). Because of this fact the milliliters of vapor produced by 1 ml of liquid anesthetic is also similar (Table II). The volume of gaseous anesthetic formed from 1 ml of liquid anesthetic can be calculated from the gas laws (Linde, 1971).
Delivery of a controlled anesthetic concentration is necessary for safe anesthesia. Stable anesthetic levels are easily produced within 10 min of the start of anesthesia. Halothane causes respiratory depression which is dose dependent. At deep anesthetic levels, ventilation becomes inadequate. This limits anesthetic delivery if the animal is spontaneously ventilating, but spontaneous respiration should not be used to regulate anesthetic depth. Halothane causes direct depression of myocardial muscle and relaxation of vascular smooth muscle.
C. W. (1991). Reversal of xylazine sedation in dogs. Vet. Rec. 128, 323-325. , ed. (1991). "Total Intravenous Anaesthesia," Monog. , Vol. 21. Elsevier, Amsterdam. Klide, A. , Calderwood, H. , and Soma, L. R. (1975). Cardiopulmonary effects of xylazine in dogs. Am. J. Vet. Res. 36, 931-935. Kolata, R. , and Rawlings, C. A. (1982). Cardiopulmonary effects of intravenous xylazine, ketamine, and atropine in the dog. Am. J. Vet. Res. 43, 2196-2198. , and Thurmon, J. C. (1979). Cardiopulmonary, hemocytologic and biochemical effects of xylazine in goats.